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Mouse Monoclonal Antibody to FABP4

  • 货号:

    20409
  • 别名:

    aP2; A-FABP; FABP4
  • 产品上架时间:

    2024-01-01
  • 应用:

  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P15090
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to FABP4

Description

Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm. It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism. FABP4 encodes the fatty acid binding protein found in adipocytes. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders.

References

1. Proc. Natl. Acad. Sci. 2006.103:6970-75.
2. Science. 1996. 274:1377-79.
3. Biochemistry. 1997.36(27):8311-7
4. Mol Cell Biochem. 2004.302(1-2):203-13

Specification

Aliases aP2; A-FABP; FABP4
Entrez GeneID 2167
Swissprot P15090
clone 9B8D
WB Predicted band size 14kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of FABP4 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

ELISA 1/10000

Product Image

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#20409