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Mouse Monoclonal Antibody to FABP4
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货号:
20409 -
别名:
aP2; A-FABP; FABP4 -
应用:
-
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P15090 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to FABP4
Description |
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Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long chain fatty acids, their coenzymes and other hydrophobic ligands and small molecules in the cytoplasm. It is thought that the role of these proteins includes fatty acid uptake, intracellular lipid transport and metabolism. FABP4 encodes the fatty acid binding protein found in adipocytes. FABP4 knockout mice fed a high-fat and high-calorie diet become obese but develop neither insulin resistance nor diabetes, suggesting that this protein might be a link between obesity and insulin resistance and diabetes A related study in humans indicated a similar pattern, suggesting that FABP4 may be a potential therapeutic target in the treatment of these disorders. |
References |
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1. Proc. Natl. Acad. Sci. 2006.103:6970-75. 2. Science. 1996. 274:1377-79. 3. Biochemistry. 1997.36(27):8311-7 4. Mol Cell Biochem. 2004.302(1-2):203-13 |
Specification |
|
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Aliases | aP2; A-FABP; FABP4 |
Entrez GeneID | 2167 |
Swissprot | P15090 |
clone | 9B8D |
WB Predicted band size | 14kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of FABP4 expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#20409

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