提醒成功

搜索
Mouse Monoclonal Antibody to CD18
-
货号:
20346 -
别名:
LAD; MF17; LCAMB; LFA-1; ITGB2 -
应用:
IF -
反应种属:
Human,Mouse -
抗体类型:
Primary antibody -
Swissprot:
P05107 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to CD18
Description |
---|
CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |
References |
---|
1. Microcirculation. 2008 Aug;15(6):555-67. 2. Mol Immunol. 2008 Feb;45(3):709-18. 3. J Biol Chem. 2007 Aug 17;282(33):24310-9. |
Specification |
|
---|---|
Aliases | LAD; MF17; LCAMB; LFA-1; ITGB2 |
Entrez GeneID | 3689 |
Swissprot | P05107 |
clone | 10E12 |
WB Predicted band size | 85kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Purified recombinant fragment of CD18 expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
IF | 1/200 - 1/1000 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#20346

相关产品


