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Mouse Monoclonal Antibody to FGB
-
货号:
20348 -
别名:
fibrinogen beta chain -
应用:
WB -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P02675 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to FGB
Description |
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Fibrinogen beta chain, also known as FGB, is a gene found in humans and most other vertebrates with a similar system of blood coagulation.It is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency. |
References |
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1. Blood. 2003 Dec 15;102(13):4413-5. 2. Arterioscler Thromb Vasc Biol. 2008 Apr;28(4):758-63. |
Specification |
|
---|---|
Aliases | fibrinogen beta chain |
Entrez GeneID | 2244 |
Swissprot | P02675 |
clone | 1F9 |
WB Predicted band size | 52kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human FGB (aa30-300) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/500 - 1/2000 |
ELISA | 1/10000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#20348

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