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Mouse Monoclonal Antibody to SOD1
-
货号:
20349 -
别名:
ALS; SOD; ALS1; IPOA; homodimer -
应用:
WB,IF,FCM -
反应种属:
Human,Mouse -
抗体类型:
Primary antibody -
Swissprot:
P00441 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to SOD1
Description |
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SOD1 (superoxide dismutase 1, soluble), also known as ALS. The protein binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis (ALS), a progressive degenerative disease of motor neurons. Rare transcript variants have been reported for this gene. |
References |
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1. Apoptosis. 2005 May;10(3):499-502. 2. Hum Mol Genet. 2008 Nov 1;17(21):3303-17. |
Specification |
|
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Aliases | ALS; SOD; ALS1; IPOA; homodimer |
Entrez GeneID | 6647 |
Swissprot | P00441 |
clone | 6F5 |
WB Predicted band size | 18kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Purified recombinant fragment of human SOD1 expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
WB | 1/500 - 1/2000 |
IF | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Western blot analysis using SOD1 mouse mAb against Hela (1), NIH/3T3 (2), A549 (3) and A431 (4) cell lysate.
- Confocal Immunofluorescence analysis of PANC-1 (left) and SKBR-3 (right) cells using SOD1 mouse mAb (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
- Confocal Immunofluorescence analysis of 3T3-L1 cells using SOD1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
- Flow cytometric analysis of A431 cells using SOD1 mouse mAb (green) and negative control (purple).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#20349

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