ISL1[20345]
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Confocal Immunofluorescence analysis of HEK293 cells trasfected with full-length ISL1-hIgGFc using ISL1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
Immunofluorescence analysis of Hela cells using ISL1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Immunohistochemical analysis of paraffin-embedded Mouse brain using ISL1 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded Rat brain using ISL1 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded Rabbit brain using ISL1 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to ISL1

  • 货号:

    20345
  • 别名:

    Isl-1; ISLET1
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC,IF
  • 反应种属:

    Human,Mouse,Rat,Rabbit
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P61371
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to ISL1

Description

ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.

References

1. Cell. 1996 Jan 26;84(2):309-20.
2. J Neurosci. 2008 Mar 26;28(13):3291-7.

Specification

Aliases Isl-1; ISLET1
Entrez GeneID 3670
Swissprot P61371
clone 1B1
WB Predicted band size 39kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat,Rabbit
Immunogen Purified recombinant fragment of human ISL1 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IHC 1/100 - 1/500
IF 1/50 - 1/500
ELISA 1/10000