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Mouse Monoclonal Antibody to ISL1
-
货号:
20344 -
别名:
Isl-1; ISLET1 -
应用:
IHC,IF -
反应种属:
Human,Mouse,Rat,Rabbit -
抗体类型:
Primary antibody -
Swissprot:
P61371 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to ISL1
Description |
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ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young. |
References |
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1. Cell. 1996 Jan 26;84(2):309-20. 2. J Neurosci. 2008 Mar 26;28(13):3291-7. |
Specification |
|
---|---|
Aliases | Isl-1; ISLET1 |
Entrez GeneID | 3670 |
Swissprot | P61371 |
clone | 1H9 |
WB Predicted band size | 39kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat,Rabbit |
Immunogen | Purified recombinant fragment of human ISL1 expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
IHC | 1/200 - 1/1000 |
IF | 1/200 - 1/1000 |
ELISA | 1/10000 |
Product Image
- Confocal Immunofluorescence analysis of HEK293 cells trasfected with full-length ISL1-hIgGFc using ISL1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
- Immunohistochemical analysis of paraffin-embedded human lung cancer (left) and cervical carcinoma (right), showing nuclear localization using ISL1 mouse mAb with DAB staining.
- Immunohistochemical analysis of paraffin-embedded Mouse brain(A)Mouse testis(B)Mouse kidney(C) using ISL1 mouse mAb with DAB staining.
- Immunohistochemical analysis of paraffin-embedded Rat brain(A)Rat testis(B)Rat kidney(C) using ISL1 mouse mAb with DAB staining.
- Immunohistochemical analysis of paraffin-embedded Rabbit testis(A)Rabbit kidney(B) using ISL1 mouse mAb with DAB staining.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#20344

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