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Western blot analysis of Filamin A Phosphorylation in WTLRRK2 lysates treated LRRK2 using Phospho-LRRK2 (Ser395) antibody.

Rabbit Polyclonal Antibody to Phospho-LRRK2 (Ser395)

  • 货号:

    P20232
  • 别名:

    AURA17; Dardarin antibody; ; Leucine rich repeat kinase 2; LRRK 2 antibody; LRRK2; LRRK2_HUMAN; PARK 8; PARK8; RIPK7; ROCO 2; ROCO2
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IF
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q5S007
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to Phospho-LRRK2 (Ser395)

Description

Positively regulates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner.

Specification

Aliases AURA17; Dardarin antibody; ; Leucine rich repeat kinase 2; LRRK 2 antibody; LRRK2; LRRK2_HUMAN; PARK 8; PARK8; RIPK7; ROCO 2; ROCO2
Entrez GeneID 120892
Swissprot Q5S007
WB Predicted band size Calculated MW: 286 kDa; Observed MW: 286 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen A synthesized peptide derived from human Phospho-LRRK2 (S935)
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500-1/1000
IF 1/50-1/200

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P20232