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Flow cytometric analysis of hela cells using ETV4 mouse mAb (green) and negative control (red).
Flow cytometric analysis of NIH3T3 cells using ETV4 mouse mAb (green) and negative control (red).
HOT

Mouse Monoclonal Antibody to ETV4

  • 货号:

    20236
  • 别名:

    HGK; NIK; PEA3
  • 产品上架时间:

    2024-03-03
  • 应用:

    FCM
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P43268
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to ETV4

Description

ETV4: ets variant gene 4 (E1A enhancer binding protein, E1AF), also known as PEA3. Several members of the Ets gene family are known to encode sequencespecific DNA binding proteins. These include mouse PU.1, mouse and human Ets-1, Drosophila E74, chicken and human Ets-2 and rat GABP-a. Each of these proteins recognizes similar motifs in DNA that share a centrally located 5'-GGAA-3' element. For instance, PEA3 binds the motif 5'-AGGAAG-3' (the PEA-3 motif), but does not bind to the sequence 5'-AGGAAC-3', recognized by PU.1, although PU.1 binds equally well to both sequences. It appears that all of the Ets proteins recognize the same central core sequence but that each protein interacts with unique sequences that flank this core. PEA3 is expressed at readily detectable levels in cells of epithelial and fibroblastic origin but is not expressed in hematopoietic cells. This is in contrast to other members of the Ets gene family, such as Ets-1, Ets-2 and Fli-1, each of which is expressed primarily in cells of hematopoietic origin.

References

1. J Biol Chem. 2005 Apr 1;280(13):12503-16.
2. Mol Carcinog. 2006 Sep;45(9):667-75.
3. Oncol Rep. 2006 Jul;16(1):153-8.

Specification

Aliases HGK; NIK; PEA3
Entrez GeneID 2118
Swissprot P43268
clone 1A2G3
WB Predicted band size 54kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of human ETV4 (aa50-109) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

FCM 1/200 - 1/400
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#20236