BMPR1A[30446A]
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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western blot analysis using BMPR1A mouse mAb against PC-3 (1), K562 (2) cell lysate, and Mouse liver (3) tissue lysate.
Flow cytometric analysis of HeLa cells using BMPR1A mouse mAb (green) and negative control (purple).
Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using BMPR1A mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human kidney tissues using BMPR1A mouse mAb with DAB staining.

Mouse Monoclonal Antibody to BMPR1A

  • 货号:

    30446A
  • 别名:

    ALK3; SKR5; CD292; ACVRLK3; 10q23del
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF,FCM
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P36894
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to BMPR1A

Description

The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

References

1.Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt 5):551-5.
2.Gastroenterology. 2011 Jul;141(1):e23-6.

Specification

Aliases ALK3; SKR5; CD292; ACVRLK3; 10q23del
Entrez GeneID 657
Swissprot P36894
clone 4B7B2
WB Predicted band size 60kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of human BMPR1A (AA: 179-378 ) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000