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Mouse Monoclonal Antibody to PSAP
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Mouse Monoclonal Antibody to PSAP
Immunofluorescence analysis of HepG2 cells using PSAP mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Mouse Monoclonal Antibody to PSAP
Flow cytometric analysis of HeLa cells using PSAP mouse mAb (green) and negative control (purple).
Mouse Monoclonal Antibody to PSAP
mmunohistochemical analysis of paraffin-embedded human pancreas tissues using PSAP mouse mAb with DAB staining.
Mouse Monoclonal Antibody to PSAP
Mouse Monoclonal Antibody to PSAP
Mouse Monoclonal Antibody to PSAP
Mouse Monoclonal Antibody to PSAP

Mouse Monoclonal Antibody to PSAP

  • 货号:

    30444
  • 别名:

    GLBA; SAP1
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC,IF,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P07602
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to PSAP

Description

This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

References

1.Biochem J. 2012 Jan 15;441(2):665-74.
2.Mol Cancer. 2010 Feb 4;9:30.

Specification

Aliases GLBA; SAP1
Entrez GeneID 5660
Swissprot P07602
clone 4D5F4
WB Predicted band size 58.1kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human PSAP (AA: 325-524 ) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
IF/ICC 1/50 - 1/500
FCM 1/200 - 1/400
ELISA 1/10000