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Mouse Monoclonal Antibody to MMP2
-
货号:
30440 -
别名:
CLG4; MONA; CLG4A; TBE-1; MMP-II -
应用:
WB -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P08253 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to MMP2
Description |
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. |
References |
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1.Br J Cancer. 2012 Apr 24;106(9):1495-8. 2.Iran J Immunol. 2011 Jun;8(2):120-6. |
Specification |
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Aliases | CLG4; MONA; CLG4A; TBE-1; MMP-II |
Entrez GeneID | 4313 |
Swissprot | P08253 |
clone | 4D1E2 |
WB Predicted band size | 73.8kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human MMP2 (AA: 242-396) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
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WB | 1/500 - 1/2000 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30440

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