4-Oct[30147]
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Western blot analysis using Oct4 mouse mAb against NTERA-2 cell lysate (1).

Mouse Monoclonal Antibody to 4-Oct

  • 货号:

    30147
  • 别名:

    OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; MGC22487; POU5F1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q01860
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to 4-Oct

Description

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12. (provided by RefSeq).Tissue specificity: Expressed in developing brain. Highest levels found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. Low levels of expression in adult tissues.

References

1. J Biol Chem. 2008 Dec 19;283(51):35825-33.
2. Dev Genes Evol. 2008 Oct;218(10):561-6.
3. Stem Cells. 2008 Sep;26(9):2419-24.

Specification

Aliases OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; MGC22487; POU5F1
Entrez GeneID 5460
Swissprot Q01860
clone 5F7
WB Predicted band size 45kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthesized peptide of human Oct4.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

WB 1/500 - 1/2000
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#30147