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Western blot analysis using SMAD5 mouse mAb against Hela (1), SK-N-SH (2), PC-12 (3), Jurkat (4), and K562 (5) cell lysate.

Immunofluorescence analysis of NTERA-2 cells using SMAD5 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Flow cytometric analysis of Jurkat cells using SMAD5 mouse mAb (green) and negative control (purple).

Immunohistochemical analysis of paraffin-embedded human brain tissues (left) and lung cancer tissues (right) using SMAD5 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to SMAD5

货号：
30150
别名：
Dwfc; JV5-1; MADH5; DKFZp781C1895; DKFZp781O1323; SMAD5
产品上架时间：
2024-01-01
应用：
WB,IHC,IF,FCM
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
Q99717
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to SMAD5

Description
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo; lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.

Description

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo; lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.

References
1. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3927-32. 2. Nat Cell Biol. 2008 May;10(5):567-74.

Specification
Aliases	Dwfc; JV5-1; MADH5; DKFZp781C1895; DKFZp781O1323; SMAD5
Entrez GeneID	4090
Swissprot	Q99717
clone	3H9
WB Predicted band size	52kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	Purified recombinant fragment of human SMAD5 expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide.