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Western blot analysis using SOX2 mouse mAb against C6(1),F9(2) cell lysate.

Immunofluorescence analysis of NTERA-2 cells using SOX2 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Immunofluorescence analysis of NIH3T3 cells using SOX2 mouse mAb (green). Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Immunofluorescence analysis of C6 cells using SOX2 mouse mAb (green)

Flow cytometric analysis of COS7 cells using SOX2 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human lung cancer tissues (left) and esophageal cancer tissues (right) using SOX2 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded Mouse brain(A) Mouse stomach(B) using SOX2 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded Rat brain(A) Rat cerebellum(B) using SOX2 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded Rabbit cerebellum(A) Rabbit spinal cord(B) using SOX2 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to SOX2

货号：
30144
别名：
ANOP3; MCOPS3
产品上架时间：
2024-03-30
应用：
WB,IHC,IF,FCM
反应种属：
Human,Mouse,Rat,Rabbit,Monkey
抗体类型：
Primary antibody
Swissprot：
P48431
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to SOX2

Description
This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

Description

This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).

References
1. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18396-401. 2. J Biol Chem. 2008 Nov 28;283(48):33730-5. 3. Nature. 2008 Oct 23;455(7216):1124-8.

Specification
Aliases	ANOP3; MCOPS3
Entrez GeneID	6657
Swissprot	P48431
clone	10F10
WB Predicted band size	34kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Rabbit,Monkey
Immunogen	Purified recombinant fragment of human SOX2 expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide.