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Mouse Monoclonal Antibody to CD217
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货号:
31620 -
别名:
IL17RA; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R -
产品上架时间:
2024-01-01 -
应用:
FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q96F46 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to CD217
Description |
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Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. |
References |
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1.Oncotarget. 2016 Feb 2;7(5):6121-35. 2.Int J Clin Exp Pathol. 2015 Jun 1;8(6):7002-8. |
Specification |
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Aliases | IL17RA; IL17R; IMD51; CANDF5; CDw217; IL-17RA; hIL-17R |
Entrez GeneID | 23765 |
Swissprot | Q96F46 |
clone | 6H1B1 |
WB Predicted band size | 96.1kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD217 (AA: extra 33-320) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31620
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