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Mouse Monoclonal Antibody to TIM3
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货号:
31622 -
别名:
HAVCR2; CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2 -
产品上架时间:
2024-01-01 -
应用:
-
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q8TDQ0 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to TIM3
Description |
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The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
References |
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1.Tumour Biol. 2016 Jun;37(6):8209-18. 2.Int Immunopharmacol. 2015 Dec;29(2):635-641. |
Specification |
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Aliases | HAVCR2; CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2 |
Entrez GeneID | 84868 |
Swissprot | Q8TDQ0 |
clone | 5A7D12 |
WB Predicted band size | 33.4kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human TIM3 (AA: 224-301) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31622
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