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Mouse Monoclonal Antibody to CD27
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货号:
31619 -
别名:
T14; S152; Tp55; TNFRSF7; S152. LPFS2 -
产品上架时间:
2024-01-01 -
应用:
FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P26842 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to CD27
Description |
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. |
References |
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1.Blood Cancer J. 2017 Jun 23;7(6):e575. 2.J Int Med Res. 2012;40(1):307-16. |
Specification |
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Aliases | T14; S152; Tp55; TNFRSF7; S152. LPFS2 |
Entrez GeneID | 939 |
Swissprot | P26842 |
clone | 3B6D3 |
WB Predicted band size | 29.1kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD27 (AA: extra 20-144) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31619
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