Mouse Monoclonal Antibody to CHRNA5

Description
The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).

References
1.Asian Pac J Cancer Prev. 2015;16(15):6685-90. 2.Nicotine Tob Res. 2016 Feb;18(2):212-20.

Specification
Aliases	LNCR2
Entrez GeneID	1138
Swissprot	P30532
clone	8F11G8
WB Predicted band size	53kDa
Host/Isotype	Mouse IgG2a
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	Purified recombinant fragment of human CHRNA5 (AA: extra 23-254) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
WB	1/500 - 1/2000
FCM	1/200 - 1/400
ELISA	1/10000