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Mouse Monoclonal Antibody to NEFM
-
货号:
31145 -
别名:
NFM; NEF3; NF-M -
应用:
IF,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P07197 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to NEFM
Description |
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Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
References |
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1.J Neuropathol Exp Neurol. 2004 Jul;63(7):759-74. 2.Neurosci Lett. 2003 Nov 13;351(2):125-9. |
Specification |
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Aliases | NFM; NEF3; NF-M |
Entrez GeneID | 4741 |
Swissprot | P07197 |
clone | 1B6B12 |
WB Predicted band size | 102.5kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human NEFM (AA: 779-916) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
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IF | 1/50 - 1/200 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Immunofluorescence analysis of Hela cells using NEFM mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
- Flow cytometric analysis of Hela cells using NEFM mouse mAb (green) and negative control (red).
- Flow cytometric analysis of Raji cells using NEFM mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31145
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