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Mouse Monoclonal Antibody to CIRBP
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Mouse Monoclonal Antibody to CIRBP
Western blot analysis using CIRBP mouse mAb against SW480 (1), PC-3 (2), A431 (3), and U251 (4) cell lysate.
Mouse Monoclonal Antibody to CIRBP
Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using CIRBP mouse mAb with DAB staining.
Mouse Monoclonal Antibody to CIRBP
Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CIRBP mouse mAb with DAB staining.
Mouse Monoclonal Antibody to CIRBP
Mouse Monoclonal Antibody to CIRBP
Mouse Monoclonal Antibody to CIRBP
Mouse Monoclonal Antibody to CIRBP

Mouse Monoclonal Antibody to CIRBP

  • 货号:

    31147
  • 别名:

    CIRP
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q14011
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to CIRBP

Description

Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3-untranslated regions (3-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.

References

1.Med Sci Monit. 2015 May 2;21:1256-60.
2.Int J Gynecol Pathol. 2003 Jul;22(3):240-7.

Specification

Aliases CIRP
Entrez GeneID 1153
Swissprot Q14011
clone 6E12B3
WB Predicted band size 18.6kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CIRBP (AA: 1-90) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ELISA 1/10000