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Mouse Monoclonal Antibody to TCF4
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Mouse Monoclonal Antibody to TCF4
Flow cytometric analysis of Hela cells using TCF4 mouse mAb (green) and negative control (red).
Mouse Monoclonal Antibody to TCF4
Mouse Monoclonal Antibody to TCF4

Mouse Monoclonal Antibody to TCF4

  • 货号:

    31149
  • 别名:

    E2-2; ITF2; PTHS; SEF2; FECD3; ITF-2; SEF-2; TCF-4
  • 产品上架时间:

    2024-01-01
  • 应用:

    FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P15884
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to TCF4

Description

This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.

References

1.J Psychiatr Res. 2015 Oct;69:95-101.
2.Haematologica. 2014 Dec;99(12):e257-9.

Specification

Aliases E2-2; ITF2; PTHS; SEF2; FECD3; ITF-2; SEF-2; TCF-4
Entrez GeneID 6925
Swissprot P15884
clone 7B1B3
WB Predicted band size 71.3kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human TCF4 (AA: 518-667) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#31149