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Mouse Monoclonal Antibody to MuRF1
-
货号:
30726 -
别名:
TRIM63; IRF; SMRZ; MURF2; RNF28 -
产品上架时间:
2024-01-01 -
应用:
IHC,IF,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q969Q1 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to MuRF1
Description |
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This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase. |
References |
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1. Liver Int. 2013 May;33(5):714-21. doi: 10.1111/liv.12128. Epub 2013 Feb 24. 2. Cell Biochem Biophys. 2011 Jun;60(1-2):113-8. |
Specification |
|
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Aliases | TRIM63; IRF; SMRZ; MURF2; RNF28 |
Entrez GeneID | 84676 |
Swissprot | Q969Q1 |
clone | 7B8E1 |
WB Predicted band size | 40.2kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide of human MuRF1 (AA: 293-304). |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
---|---|
IHC | 1/200 - 1/1000 |
IF | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
- Immunofluorescence analysis of Hela cells using MuRF1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
- Flow cytometric analysis of Hela cells using MuRF1 mouse mAb (green) and negative control (red).
- Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using MuRF1 mouse mAb with DAB staining.
- Immunohistochemical analysis of paraffin-embedded human muscle tissues using MuRF1 mouse mAb with DAB staining.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30726
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