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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Immunofluorescence analysis of Hela cells using PDGFRA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Immunofluorescence analysis of NIH/3T3 cells using PDGFRA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Immunofluorescence analysis of COS-7 cells using PDGFRA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Flow cytometric analysis of Hela cells using PDGFRA mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to PDGFRA

  • 货号:

    30728
  • 别名:

    CD140A; PDGFR2; PDGFR-2; RHEPDGFRA
  • 产品上架时间:

    2024-01-01
  • 应用:

    IF,FCM
  • 反应种属:

    Human,Mouse,Monkey
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P16234
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to PDGFRA

Description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

References

1. Stem Cells Dev. 2013 Jul 1;22(13):1932-43.
2. Cancer Biol Ther. 2012 Dec;13(14):1384-9.

Specification

Aliases CD140A; PDGFR2; PDGFR-2; RHEPDGFRA
Entrez GeneID 5156
Swissprot P16234
clone 8E12F2
WB Predicted band size 122.7kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Monkey
Immunogen Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IF 1/50 - 1/500
FCM 1/200 - 1/400
ELISA 1/10000