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Mouse Monoclonal Antibody to PDGFRA
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货号:
30728 -
别名:
CD140A; PDGFR2; PDGFR-2; RHEPDGFRA -
产品上架时间:
2024-01-01 -
应用:
IF,FCM -
反应种属:
Human,Mouse,Monkey -
抗体类型:
Primary antibody -
Swissprot:
P16234 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to PDGFRA
Description |
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This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. |
References |
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1. Stem Cells Dev. 2013 Jul 1;22(13):1932-43. 2. Cancer Biol Ther. 2012 Dec;13(14):1384-9. |
Specification |
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Aliases | CD140A; PDGFR2; PDGFR-2; RHEPDGFRA |
Entrez GeneID | 5156 |
Swissprot | P16234 |
clone | 8E12F2 |
WB Predicted band size | 122.7kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Monkey |
Immunogen | Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
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IF | 1/50 - 1/500 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
- Immunofluorescence analysis of Hela cells using PDGFRA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
- Immunofluorescence analysis of NIH/3T3 cells using PDGFRA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
- Immunofluorescence analysis of COS-7 cells using PDGFRA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
- Flow cytometric analysis of Hela cells using PDGFRA mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30728
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