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Mouse Monoclonal Antibody to PDGFRA
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Mouse Monoclonal Antibody to PDGFRA
Immunofluorescence analysis of Hela cells using PDGFRA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Mouse Monoclonal Antibody to PDGFRA
Immunofluorescence analysis of NIH/3T3 cells using PDGFRA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Mouse Monoclonal Antibody to PDGFRA
Immunofluorescence analysis of COS-7 cells using PDGFRA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Mouse Monoclonal Antibody to PDGFRA
Flow cytometric analysis of Hela cells using PDGFRA mouse mAb (green) and negative control (red).
Mouse Monoclonal Antibody to PDGFRA
Mouse Monoclonal Antibody to PDGFRA
Mouse Monoclonal Antibody to PDGFRA
Mouse Monoclonal Antibody to PDGFRA
Mouse Monoclonal Antibody to PDGFRA

Mouse Monoclonal Antibody to PDGFRA

  • 货号:

    30728
  • 别名:

    CD140A; PDGFR2; PDGFR-2; RHEPDGFRA
  • 产品上架时间:

    2024-01-01
  • 应用:

    IF,FCM
  • 反应种属:

    Human,Mouse,Monkey
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P16234
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to PDGFRA

Description

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

References

1. Stem Cells Dev. 2013 Jul 1;22(13):1932-43.
2. Cancer Biol Ther. 2012 Dec;13(14):1384-9.

Specification

Aliases CD140A; PDGFR2; PDGFR-2; RHEPDGFRA
Entrez GeneID 5156
Swissprot P16234
clone 8E12F2
WB Predicted band size 122.7kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Monkey
Immunogen Purified recombinant fragment of human PDGFRA (AA: 361-528) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IF/ICC 1/50 - 1/500
FCM 1/200 - 1/400
ELISA 1/10000