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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western blot analysis using CASP-7 mouse mAb against Jurkat (1), HEK293 (2), MOLT4 (3), MCF-7 (4), PC-12 (5) cell lysate.
Flow cytometric analysis of MCF-7 cells using CASP-7 mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CASP-7 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to CASP-7

  • 货号:

    30727
  • 别名:

    MCH3; CMH-1; LICE2; CASP7; ICE-LAP3
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P55210
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to CASP-7

Description

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

References

1. Lung Cancer. 2009 Jul;65(1):19-24.
2. Genes Cells. 2008 Jun;13(6):609-21.

Specification

Aliases MCH3; CMH-1; LICE2; CASP7; ICE-LAP3
Entrez GeneID 840
Swissprot P55210
clone 4D10B2
WB Predicted band size 34.3kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CASP-7 (AA: 29-198) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000