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Mouse Monoclonal Antibody to ITGA2B
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Mouse Monoclonal Antibody to ITGA2B
Flow cytometric analysis of HL60 cells using ITGA2B mouse mAb (green) and negative control (purple).
Mouse Monoclonal Antibody to ITGA2B
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using ITGA2B mouse mAb with DAB staining.
Mouse Monoclonal Antibody to ITGA2B
Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using ITGA2B mouse mAb with DAB staining.
Mouse Monoclonal Antibody to ITGA2B
Mouse Monoclonal Antibody to ITGA2B
Mouse Monoclonal Antibody to ITGA2B
Mouse Monoclonal Antibody to ITGA2B

Mouse Monoclonal Antibody to ITGA2B

  • 货号:

    30485A
  • 别名:

    GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P08514
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to ITGA2B

Description

ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

References

1. Pediatr Blood Cancer. 2012 Aug;59(2):335-8.
2. Blood. 2011 Dec 1;118(23):5996-6005.

Specification

Aliases GT; GTA; CD41; GP2B; HPA3; CD41B; GPIIb; BDPLT2
Entrez GeneID 3674
Swissprot P08514
clone 2E10C9
WB Predicted band size 113.4kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human ITGA2B (AA: 45-149) expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000