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Rabbit Polyclonal Antibody to LOK (C-term E707)
-
货号:
P30042 -
别名:
Serine/threonine-protein kinase 10, Lymphocyte-oriented kinase, STK10, LOK -
应用:
WB,IHC-P -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
O94804 -
规格:
-
数量:
-+ -
说明书:
目录价¥1980
Rabbit Polyclonal Antibody to LOK (C-term E707)
Description |
|---|
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. |
Specification |
|
|---|---|
| Aliases | Serine/threonine-protein kinase 10, Lymphocyte-oriented kinase, STK10, LOK |
| Entrez GeneID | 6793 |
| Swissprot | O94804 |
| WB Predicted band size | 112.1kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This LOK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human LOK. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
Product Image
- The anti-LOK Pab (Cat. #P30042) is used in Western blot to detect LOK in Jurkat cell lysate.
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#P30042
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