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Mouse Monoclonal Antibody to KEAP1
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Mouse Monoclonal Antibody to KEAP1
Western blot analysis using KEAP1 mouse mAb against NIH3T3 (1), and A549 (2) cell lysate.
Mouse Monoclonal Antibody to KEAP1
Immunofluorescence analysis of HeLa cells using KEAP1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Mouse Monoclonal Antibody to KEAP1
Flow cytometric analysis of HepG2 cells using KEAP1 mouse mAb (green) and negative control (purple).
Mouse Monoclonal Antibody to KEAP1
Mouse Monoclonal Antibody to KEAP1
Mouse Monoclonal Antibody to KEAP1
Mouse Monoclonal Antibody to KEAP1

Mouse Monoclonal Antibody to KEAP1

  • 货号:

    30431
  • 别名:

    INrf2; KLHL19
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IF,FCM
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q14145
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to KEAP1

Description

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.





References

1.Cell Signal. 2010 Nov;22(11):1645-54.
2.Mol Cancer Ther. 2010 Feb;9(2):336-46.

Specification

Aliases INrf2; KLHL19
Entrez GeneID 9817
Swissprot Q14145
clone 1F10B6
WB Predicted band size 69.7kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of human KEAP1 (AA: 380-624) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IF/ICC 1/50
FCM 1/200 - 1/400
ELISA 1/10000