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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Western blot analysis using KEAP1 mouse mAb against NIH3T3 (1), and A549 (2) cell lysate.

Immunofluorescence analysis of HeLa cells using KEAP1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Flow cytometric analysis of HepG2 cells using KEAP1 mouse mAb (green) and negative control (purple).

Mouse Monoclonal Antibody to KEAP1

货号：
30431
别名：
INrf2; KLHL19
产品上架时间：
2024-01-01
应用：
WB,IF,FCM
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q14145
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to KEAP1

Description
This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Description

This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.

References
1.Cell Signal. 2010 Nov;22(11):1645-54. 2.Mol Cancer Ther. 2010 Feb;9(2):336-46.

Specification
Aliases	INrf2; KLHL19
Entrez GeneID	9817
Swissprot	Q14145
clone	1F10B6
WB Predicted band size	69.7kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Purified recombinant fragment of human KEAP1 (AA: 380-624) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide.