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Mouse Monoclonal Antibody to NFKBIB
-
货号:
30082 -
别名:
IKBB; TRIP9; NFKBIB -
应用:
WB -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q15653 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to NFKBIB
Description |
|---|
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined. |
References |
|---|
| 1. Mol Cell Biol. 2004 Apr;24(7):3048-56. 2. J Biol Chem. 2004 Oct 15;279(42):44030-8. 3. J Bone Miner Res. 2009 Dec;24(12):2039-49. |
Specification |
|
|---|---|
| Aliases | IKBB; TRIP9; NFKBIB |
| Entrez GeneID | 4793 |
| Swissprot | Q15653 |
| clone | 7B4 |
| WB Predicted band size | 45kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human NFKBIB expressed in E. Coli. |
| Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| ELISA | 1/10000 |
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30082
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