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Flow cytometric analysis of COS7 cells using ETV1 mouse mAb (green) and negative control (red).
Flow cytometric analysis of hela cells using ETV1 mouse mAb (green) and negative control (red).
HOT

Mouse Monoclonal Antibody to ETV1

  • 货号:

    20281
  • 别名:

    ER81
  • 产品上架时间:

    2024-03-03
  • 应用:

    FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P50549
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to ETV1

Description

ETV1: ets variant gene 1. Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All of the Ets proteins recognize the same central core sequence but each protein interacts with unique sequences that flank this core. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung and heart. ER81 is also moderately expressed in spleen, pancreas, colon and small intestine. During development, ER81 displays a unique expression patterns which suggests that this transcriptional factor might play an important role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits ER81.

References

1. Neoplasia. 2006 Oct;8(10):826-32.
2. Cancer Genet Cytogenet. 2008 May;183(1):21-7.

Specification

Aliases ER81
Entrez GeneID 2115
Swissprot P50549
clone 1C8B6
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of ETV1 (aa1-191) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

FCM 1/200 - 1/400
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#20281