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Immunohistochemical analysis of paraffin-embedded human breast carcinoma(A), lung cancer(B) and normal colon tissue(C), showing cytoplasmic localization with DAB staining using KRT19 mouse mAb.

Mouse Monoclonal Antibody to Cytokeratin 19

货号：
20283
别名：
CK19; K1CS; MGC15366; KRT19
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P08727
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to Cytokeratin 19

Description
Cytokeratin 19, also known as KRT19, CK19, CK19, K1CS, MGC15366. Entrez Protein NP_002267. It is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.

Description

Cytokeratin 19, also known as KRT19, CK19, CK19, K1CS, MGC15366. Entrez Protein NP_002267. It is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.

References
1. Lung Cancer. 2007 Dec;58(3):369-75. 2. Endocr Pract. 2008 Mar;14(2):168-74.

Specification
Aliases	CK19; K1CS; MGC15366; KRT19
Entrez GeneID	3880
Swissprot	P08727
clone	9H8G6
WB Predicted band size	44kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of Cytokeratin 19 (aa80-400) expressed in E. Coli.
Formulation	Ascitic fluid containing 0.03% sodium azide.