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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Immunofluorescence analysis of Hela cells using IRF3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Immunofluorescence analysis of NIH/3T3 cells using IRF3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Immunofluorescence analysis of RSC96 cells using IRF3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using IRF3 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human lung cancer tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human colon cancer tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded mouse liver tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded mouse kidney tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rat liver tissues using IRF3 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded rat kidney tissues using IRF3 mouse mAb with DAB staining.

试 HOT

Mouse Monoclonal Antibody to IRF3

货号：
32414
别名：
IIAE7
产品上架时间：
2024-01-01
应用：
IHC,IF,FCM
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
Q14653
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to IRF3

Description
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.

Description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7.

References
1.J Immunol. 2020 Oct 15;205(8):1981-1989. 2.Viruses. 2019 Mar 12;11(3):246.

Specification
Aliases	IIAE7
Entrez GeneID	3661
Swissprot	Q14653
clone	2A10A8
WB Predicted band size	47.2kDa
Host/Isotype	Mouse IgG2b
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Purified recombinant fragment of human IRF3 (AA: 1-150) expressed in HEK293-6e cells supernatant.
Formulation	Purified antibody in PBS with 0.05% sodium azide