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Mouse Monoclonal Antibody to BCL10
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货号:
31535 -
别名:
CLAP; mE10; CIPER; IMD37; c-E10; CARMEN -
应用:
FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
O95999 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to BCL10
Description |
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This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. |
References |
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1.Cell Cycle. 2016;15(1):84-94. 2.Pathol Int. 2013 Mar;63(3):176-82. |
Specification |
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Aliases | CLAP; mE10; CIPER; IMD37; c-E10; CARMEN |
Entrez GeneID | 8915 |
Swissprot | O95999 |
clone | 3C11F4 |
WB Predicted band size | 26.3kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human BCL10 (AA: 98-234) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31535
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