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Western blot analysis of Phospho-EGFR (Tyr1173) in Hela, A549 lysates using Phospho-EGFR (Tyr1173) antibody.
Immunocytochemistry analysis of Phospho-EGFR (Tyr1173) (green) in Hela using Phospho-EGFR (Tyr1173) antibody,and DAPI(blue)
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using EGFR (Phospho-Tyr1173) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Rabbit Monoclonal Antibody to Phospho-EGFR (Tyr1173)

  • 货号:

    P20172
  • 别名:

    EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IP,IHC,IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P00533
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Monoclonal Antibody to Phospho-EGFR (Tyr1173)

Description

EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Specification

Aliases EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Entrez GeneID 1956
Swissprot P00533
WB Predicted band size Calculated MW: 134 kDa; Observed MW: 175 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr1173 of human EGFR
Formulation Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IP 1/10-1/20
IHC 1/50-1/100
IF 1/50-1/200