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Rabbit Monoclonal Antibody to Phospho-IGF1 Receptor (Tyr1166)
-
货号:
P20124 -
别名:
IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221 -
应用:
WB,IP -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
P08069 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Rabbit Monoclonal Antibody to Phospho-IGF1 Receptor (Tyr1166)
Description |
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This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
Specification |
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Aliases | IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221 |
Entrez GeneID | 3480 |
Swissprot | P08069 |
WB Predicted band size | Calculated MW: 155 kDa; Observed MW: 95 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human INSR/IGF-1R |
Formulation | Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol. |
Application |
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---|---|
WB | 1/500-1/1000 |
IP | 1/10-1/20 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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