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Immunofluorescence staining of methanol-fixed Hela cells using ABL2 mouse mAb showing cytoplasm localization.

Mouse Monoclonal Antibody to ABL2

  • 货号:

    20125
  • 别名:

    ARG; ABLL; FLJ22224; FLJ31718; FLJ41441
  • 产品上架时间:

    2024-01-01
  • 应用:

    IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P42684
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to ABL2

Description

ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization,c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl.

References

1. Yoshimi I, Takashi I, Tsuneyuki O, et al. Blood. 2000; 95(6): 2126-2131.
2. Scheijen, B. and Griffin, J.D. Oncogene. 2002); 21:3314-33.

Specification

Aliases ARG; ABLL; FLJ22224; FLJ31718; FLJ41441
Entrez GeneID 27
Swissprot P42684
clone 1H1B11
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of ABL2 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.

Application

IF 1/200 - 1/1000
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#20125