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Mouse Monoclonal Antibody to ABL2
-
货号:
20125 -
别名:
ARG; ABLL; FLJ22224; FLJ31718; FLJ41441 -
产品上架时间:
2024-01-01 -
应用:
IF -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P42684 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to ABL2
Description |
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ABL2(ARG, Abelson-related gene) is a cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of the proteins includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2 is expressed in both normal and tumor cells. The ABL2 gene product is expressed as two variants bearing different amino termini, both approximately 12-kb in length. c-Abl shows both cytoplasmic and nuclear localization,c-Abl is involved in two different chromosomal translocations present in human leukemias, which generate Bcr-Abl and TEL-Abl. |
References |
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1. Yoshimi I, Takashi I, Tsuneyuki O, et al. Blood. 2000; 95(6): 2126-2131. 2. Scheijen, B. and Griffin, J.D. Oncogene. 2002); 21:3314-33. |
Specification |
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Aliases | ARG; ABLL; FLJ22224; FLJ31718; FLJ41441 |
Entrez GeneID | 27 |
Swissprot | P42684 |
clone | 1H1B11 |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of ABL2 expressed in E. Coli. |
Formulation | Ascitic fluid containing 0.03% sodium azide. |
Application |
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IF | 1/200 - 1/1000 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#20125
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