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Mouse Monoclonal Antibody to CD197
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货号:
31346 -
别名:
BLR2; EBI1; CCR-7; CCR7; CDw197; CMKBR7; CC-CKR-7 -
应用:
WB,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P32248 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to CD197
Description |
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The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. |
References |
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1.Gastric Cancer. 2017 Mar;20(2):235-245. 2.J Surg Oncol. 2015 Jul;112(1):86-92. |
Specification |
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Aliases | BLR2; EBI1; CCR-7; CCR7; CDw197; CMKBR7; CC-CKR-7 |
Entrez GeneID | 1236 |
Swissprot | P32248 |
clone | 7A5A9 |
WB Predicted band size | 42.9kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD197 (AA: extra mix) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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WB | 1/500 - 1/2000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Western blot analysis using CD197 mouse mAb against C6 (1) cell lysate.
- Flow cytometric analysis of HL-60 cells using CD197 mouse mAb (green) and negative control (red).
- Flow cytometric analysis of K562 cells using CD197 mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31346
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