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Mouse Monoclonal Antibody to CD104
-
货号:
31347 -
别名:
ITGB4; GP150 -
产品上架时间:
2024-01-01 -
应用:
WB,IHC,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P16144 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to CD104
Description |
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Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
References |
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1.Sci Rep. 2015 Nov 17;5:16529. 2.Acta Derm Venereol. 2015 Jan;95(1):112-3. |
Specification |
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Aliases | ITGB4; GP150 |
Entrez GeneID | 3691 |
Swissprot | P16144 |
clone | 5G3G5 |
WB Predicted band size | 202.2kDa |
Host/Isotype | Mouse IgG2a |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD104 (AA: extra 29-206) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
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WB | 1/500 - 1/2000 |
IHC | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Western blot analysis using CD104 mouse mAb against A549 (1), A431 (2), and SW620 (3) cell lysate.
- Flow cytometric analysis of HL-60 cells using CD104 mouse mAb (green) and negative control (red).
- Immunohistochemical analysis of paraffin-embedded human stomach cancer tissues using CD104 mouse mAb with DAB staining.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31347
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