提醒成功
搜索
Mouse Monoclonal Antibody to GRM1
-
货号:
31284 -
别名:
MGLU1; GPRC1A; MGLUR1; SCAR13; PPP1R85 -
产品上架时间:
2024-01-01 -
应用:
-
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q13255 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to GRM1
Description |
---|
This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. |
References |
---|
1.Breast Cancer Res Treat. 2015 May;151(1):57-73. 2.PLoS One. 2013 Jul 26;8(7):e69851. |
Specification |
|
---|---|
Aliases | MGLU1; GPRC1A; MGLUR1; SCAR13; PPP1R85 |
Entrez GeneID | 2911 |
Swissprot | Q13255 |
clone | 5E12D8 |
WB Predicted band size | 132.4kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human GRM1 (AA: extra 387-486) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
---|---|
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31284
相关产品