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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Mouse Monoclonal Antibody to GRM1

  • 货号:

    31284
  • 别名:

    MGLU1; GPRC1A; MGLUR1; SCAR13; PPP1R85
  • 产品上架时间:

    2024-01-01
  • 应用:

  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q13255 
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to GRM1

Description

This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

References

1.Breast Cancer Res Treat. 2015 May;151(1):57-73.
2.PLoS One. 2013 Jul 26;8(7):e69851.

Specification

Aliases MGLU1; GPRC1A; MGLUR1; SCAR13; PPP1R85
Entrez GeneID 2911
Swissprot Q13255 
clone 5E12D8
WB Predicted band size 132.4kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human GRM1 (AA: extra 387-486) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#31284