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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using PAK3 mouse mAb against Hela (1), SK-N-SH (2), and T47D (3) cell lysate.
Mouse Monoclonal Antibody to PAK3
-
货号：
31173 -
别名：
ARA; bPAK; MRX30; MRX47; OPHN3; PAK-3; PAK3beta; beta-PAK -
应用：
WB -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
O75914 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Mouse Monoclonal Antibody to PAK3
Description |
|---|
The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. |
References |
|---|
| 1.J Mol Biol. 2014 Oct 23;426(21):3520-38. 2.J Biol Chem. 2011 Nov 18;286(46):40044-59. |
Specification |
|
|---|---|
| Aliases | ARA; bPAK; MRX30; MRX47; OPHN3; PAK-3; PAK3beta; beta-PAK |
| Entrez GeneID | 5063 |
| Swissprot | O75914 |
| clone | 4G8A5 |
| WB Predicted band size | 62.3kDa |
| Host/Isotype | Mouse IgG1 |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human PAK3 (AA: 1-100) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| WB | 1/500 - 1/2000 |
| ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31173
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