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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using CDC37 mouse mAb against K562 (1), LNcap (2), A431 (3), HEK293 (4), and C2C12 (5) cell lysate.
Flow cytometric analysis of K562 cells using CDC37 mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to CDC37

  • 货号:

    31158
  • 别名:

    P50CDC37
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,FCM
  • 反应种属:

    Human,Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q16543
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to CDC37

Description

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

References

1.Liver Int. 2015 Apr;35(4):1403-15.
2.Oncogene. 2009 Jan 15;28(2):157-69.

Specification

Aliases P50CDC37
Entrez GeneID 11140
Swissprot Q16543
clone 6B3B7
WB Predicted band size 44.5kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Purified recombinant fragment of human CDC37 (AA: 241-378) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000