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Mouse Monoclonal Antibody to ATF4
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Mouse Monoclonal Antibody to ATF4
Western blot analysis using ATF4 mouse mAb against K562 (1), A431 (2), Hela (3), HEK293 (4), and Ramos (5) cell lysate.
Mouse Monoclonal Antibody to ATF4
Immunohistochemical analysis of paraffin-embedded human breast cancer tissues using ATF4 mouse mAb with DAB staining.
Mouse Monoclonal Antibody to ATF4
Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using ATF4 mouse mAb with DAB staining.
Mouse Monoclonal Antibody to ATF4
Mouse Monoclonal Antibody to ATF4
Mouse Monoclonal Antibody to ATF4
Mouse Monoclonal Antibody to ATF4

Mouse Monoclonal Antibody to ATF4

  • 货号:

    31162
  • 别名:

    CREB2; TXREB; CREB-2; TAXREB67
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P18848
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to ATF4

Description

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

References

1.Cell. 2014 Aug 28;158(5):1159-72.
2.Tumour Biol. 2014 Jan;35(1):765-71.

Specification

Aliases CREB2; TXREB; CREB-2; TAXREB67
Entrez GeneID 468
Swissprot P18848
clone 2A6F12
WB Predicted band size 38.6kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human ATF4 (AA: 212-351) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
ELISA 1/10000