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Mouse Monoclonal Antibody to APBA2
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货号:
31157 -
别名:
X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091 -
产品上架时间:
2024-01-01 -
应用:
IF -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q99767 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to APBA2
Description |
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The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. |
References |
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1.Neuroreport. 2012 Feb 15;23(3):146-51. 2.Autism Res. 2009 Dec;2(6):359-64. |
Specification |
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Aliases | X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091 |
Entrez GeneID | 321 |
Swissprot | Q99767 |
clone | 1C12A4 |
WB Predicted band size | 82.5kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human APBA2 (AA: 15-158) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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IF | 1/50 - 1/200 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Immunofluorescence analysis of Hela cells using APBA2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31157
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