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Mouse Monoclonal Antibody to NR1I2
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Mouse Monoclonal Antibody to NR1I2
Flow cytometric analysis of HepG2 cells using NR1I2 mouse mAb (green) and negative control (red).
Mouse Monoclonal Antibody to NR1I2
Mouse Monoclonal Antibody to NR1I2

Mouse Monoclonal Antibody to NR1I2

  • 货号:

    31117
  • 别名:

    BXR; PAR; PRR; PXR; SAR; SXR; ONR1; PAR1; PAR2; PARq
  • 产品上架时间:

    2024-01-01
  • 应用:

    FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    O75469
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to NR1I2

Description

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.

References

1.Int J Mol Sci. 2014 Sep 29;15(10):17457-68.
2.J Periodontal Res. 2012 Apr;47(2):174-9.

Specification

Aliases BXR; PAR; PRR; PXR; SAR; SXR; ONR1; PAR1; PAR2; PARq
Entrez GeneID 8856
Swissprot O75469
clone 6H11D8
WB Predicted band size 49.8kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human NR1I2 (AA:1-142) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

FCM 1/200 - 1/400
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#31117