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Mouse Monoclonal Antibody to SEC31A
-
货号:
31004 -
别名:
ABP125; ABP130; HSPC275; HSPC334; SEC31L1 -
应用:
IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
O94979 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180

Mouse Monoclonal Antibody to SEC31A
Description |
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The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. |
References |
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1.J Biol Chem. 2015 Feb 20;290(8):4981-93. 2.Blood. 2011 Apr 14;117(15):4056-64. |
Specification |
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Aliases | ABP125; ABP130; HSPC275; HSPC334; SEC31L1 |
Entrez GeneID | 22872 |
Swissprot | O94979 |
clone | 5D12C6 |
WB Predicted band size | 133kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human SEC31A (AA: 429-571) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
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IHC | 1/200 - 1/1000 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31004

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