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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Western blot analysis using ALDH6A1 mouse mAb against Jurkat (1), HEK293 (2), Hela (3), MCF-7 (4), and LNcap (5) cell lysate.

Immunofluorescence analysis of Hela cells using ALDH6A1 mouse mAb. Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.

Immunofluorescence analysis of Hela cells using ALDH6A1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using ALDH6A1 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using ALDH6A1 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues using ALDH6A1 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to ALDH6A1

货号：
30974
别名：
MMSDH; MMSADHA
产品上架时间：
2024-01-01
应用：
WB,IHC,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q02252
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to ALDH6A1

Description
This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.

Description

This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.

References
1.Orphanet J Rare Dis. 2013 Jul 9;8:98. 2.J Inherit Metab Dis. 2012 May;35(3):437-42.

Specification
Aliases	MMSDH; MMSADHA
Entrez GeneID	4329
Swissprot	Q02252
clone	6H9B8
WB Predicted band size	57.8kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human ALDH6A1 (AA: 1-195) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide