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Mouse Monoclonal Antibody to TCL1A
Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Mouse Monoclonal Antibody to TCL1A
Flow cytometric analysis of Hela cells using TCL1A mouse mAb (green) and negative control (red).
Mouse Monoclonal Antibody to TCL1A
Mouse Monoclonal Antibody to TCL1A

Mouse Monoclonal Antibody to TCL1A

  • 货号:

    30715
  • 别名:

    TCL1
  • 产品上架时间:

    2024-01-01
  • 应用:

    FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P56279
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to TCL1A

Description

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).

References

1. Blood. 2012 Aug 23;120(8):1613-23.
2. Histopathology. 2010 Jul;57(1):152-7.

Specification

Aliases TCL1
Entrez GeneID 8115
Swissprot P56279
clone 2E3A5
WB Predicted band size 13.5kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human TCL1A (AA: 10-104) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

FCM 1/200 - 1/400
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#30715