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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Western blot analysis using XRCC6 mouse mAb against Hela (1), PC-2 (2), A549 (3), A431 (4), HepG2 (5), K562 (6) cell lysate.

Immunofluorescence analysis of MCF-7 cells using XRCC6 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of A431 cells using XRCC6 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human endometrial cancer tissues using XRCC6 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using XRCC6 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to XRCC6

货号：
30686
别名：
ML8; KU70; TLAA; CTC75; CTCBF; G22P1
产品上架时间：
2024-01-01
应用：
WB,IHC,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P12956
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to XRCC6

Description
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Description

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

References
1. Clin Cancer Res. 2013 Mar 15;19(6):1547-56. 2. Mol Carcinog. 2012 Oct;51 Suppl 1:E183-90.

Specification
Aliases	ML8; KU70; TLAA; CTC75; CTCBF; G22P1
Entrez GeneID	2547
Swissprot	P12956
clone	2F7F5
WB Predicted band size	69.8kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human XRCC6 (AA: 6-214) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide.