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Rabbit Polyclonal Antibody to Mouse Mavs (N-term)

MOUSE Mavs Antibody (N-term) (Cat. #P32350) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the MOUSE Mavs antibody detected the MOUSE Mavs protein (arrow).

Rabbit Polyclonal Antibody to Mouse Mavs (N-term)

货号：
P32350
别名：
Mitochondrial antiviral-signaling protein, MAVS, CARD adapter inducing interferon beta, Cardif, Interferon beta promoter stimulator protein 1, IPS-1, Virus-induced-signaling adapter, VISA, Mavs, Ips1, Visa
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Mouse
抗体类型：
Primary antibody
Swissprot：
Q8VCF0
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to Mouse Mavs (N-term)

Description
Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).

Description

Required for innate immune defense against viruses. Acts downstream of DDX58 and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). May activate the same pathways following detection of extracellular dsRNA by TLR3. May protect cells from apoptosis (By similarity).

Specification
Aliases	Mitochondrial antiviral-signaling protein, MAVS, CARD adapter inducing interferon beta, Cardif, Interferon beta promoter stimulator protein 1, IPS-1, Virus-induced-signaling adapter, VISA, Mavs, Ips1, Visa
Entrez GeneID	228607
Swissprot	Q8VCF0
WB Predicted band size	53.4kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Mouse
Immunogen	This Mouse Mavs antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse Mavs.
Formulation	Purified antibody in PBS with 0.05% sodium azide.