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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Immunofluorescence analysis of Hela cells using LRRK2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using LRRK2 mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to LRRK2

货号：
32352
别名：
PARK8; RIPK7; ROCO2; AURA17; DARDARIN
产品上架时间：
2024-01-01
应用：
IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q5S007
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to LRRK2

Description
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

Description

This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

References
1.Neurodegener Dis. 2020;20(2-3):65-72. 2.Cells. 2020 Oct 31;9(11):2394.

Specification
Aliases	PARK8; RIPK7; ROCO2; AURA17; DARDARIN
Entrez GeneID	120892
Swissprot	Q5S007
clone	2A2A8
WB Predicted band size	286kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human LRRK2 (AA: 300-530) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide