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Mouse Casc5 Antibody (C-term) (Cat. #P32172) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Casc5 antibody detected the Casc5 protein (arrow).

Rabbit Polyclonal Antibody to Mouse Casc5

  • 货号:

    P32172
  • 别名:

    Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Mouse
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q66JQ7
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to Mouse Casc5

Description

Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Directly links spindle checkpoint proteins BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore (By similarity).

Specification

Aliases Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1
Swissprot Q66JQ7
WB Predicted band size 179.3kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Mouse
Immunogen This Mouse Casc5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1557-1583 amino acids from the C-terminal region of mouse Casc5.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/1000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P32172